childhood-trauma

In Mice, Early-Life Stress Writes a Molecular Mark Onto the Brain's Reward Neurons. Turn One Enzyme Down, and It Never Sets

Early-life stress raises an enzyme called SETD7 in the brain's dopamine neurons, loosening the DNA around stress genes so they fire too easily into adulthood. When researchers blocked it in mice, the stressed animals did not develop the same anxiety-like stress sensitivity, and stayed as social and