tau
4 stories tagged "tau"
Anti-Tau Alzheimer's Drugs Keep Hitting Their Target and Missing the Disease
Tau is the new headliner at the Alzheimer's conference, but the anti-tau antibodies keep proving they bind the protein while doing nothing for patients. The clearest win so far is a blood test.
Brain & AgingAlzheimer's Hitches a Ride on a Virus Your Neurons Tamed for Memory
In mice and in human Alzheimer's brains, toxic tau rides a protein called Arc, a virus your neurons domesticated for memory, from sick cells into healthy ones. Delete Arc and the spread nearly stops.
Brain & AgingThe Alzheimer's Field Spent Decades Trying to Destroy These Droplets. A Baylor Lab Says the Droplets Were Never the Problem.
A Baylor lab reports that tubulin redirects Tau and alpha-synuclein away from toxic clumping in the test tube. It is elegant mechanism work, and not yet a drug, an animal, or a person.
Brain & AgingThe amyloid-versus-tau war in Alzheimer's might be the wrong fight
A four-person UC Riverside chemistry group argues amyloid beta and tau compete for the same microtubule binding sites, a unifying mechanism that cuts under Alzheimer's research's three-decade amyloid-versus-tau fight.