t-cells
3 stories tagged "t-cells"
Autoimmune & Inflammation
Donor T Cells Cross Into the Gut Lining and Become Resident Killers That Won't Leave
Columbia researchers tracked more than 51,000 donor T-cell clones across two years and found the ones tied to the worst graft-versus-host disease change identity depending on where they land in the gut, and spike in the blood weeks before symptoms show.
CancerOne Protein Keeps Your T Cells in the Fight. The Same Protein Feeds Autoimmune Disease.
In mice, deleting the LEF1 gene collapsed the reserve T cells that sustain the fight against chronic infection and cancer. The same deletion protected against autoimmune diabetes.
Infectious DiseaseMost People's Bodies Quietly Beat TB. The Ones Who Lose Are Drowning Their Own T Cells.
A new single-cell study of the airways of TB-exposed people finds that progression to disease tracks with a neutrophil flood that smothers protective T cells, with type I interferon as the switch.