sex-differences
2 stories tagged "sex-differences"
Metabolic & Weight
A Brain Protein Made Female Mice Overeat Fat, and the $441,000 Obesity Drug Worked Weakest on Them
Dietary fat switches on an appetite-protecting brain protein in male mice but not females. Delete it and the females overeat fat, gain more weight, and setmelanotide, the $441,000-a-year MC4R obesity drug, loses much of its appetite-suppressing punch on them.
Brain & AgingA 272,000-Person Study Linked Higher Tyrosine to Shorter Lifespans in Men. The Supplement Aisle Sells It for Focus.
A UK Biobank analysis of 272,475 people using Mendelian randomization links higher blood tyrosine to about 0.91 fewer years of life in men, with no signal in women. The amino acid is sold widely as a focus and stress supplement. The study measured blood levels, not pills.