Thursday, August 27, 2026 Evidence-led medical research news
The First Cohort
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brain-aging

11 stories tagged "brain-aging"

Brain & Aging

In Depressed Brains, the New-Neuron Supply Had Stalled Where Fresh Pain Gets Sorted From Old

Columbia researchers mapped nearly 500,000 cells from postmortem brains and found the depressed ones showed a stalled supply of new hippocampal neurons, the cells thought to keep a fresh setback from merging with every old one.

Brain & Aging

A Brain Clock Says Your Fourth Language Is Worth 13 Years. Nobody's Published the Proof.

The 13-years-younger figure comes from a conference talk with no paper behind it, and the sturdier study underneath still can't tell you whether the languages did anything at all.

Brain & Aging

Any Amount of Midlife Movement Tracked With Slower Brain Decline, Most Clearly in Mexican American Adults

In a San Antonio cohort followed since 1979, any physical activity in midlife tracked with slower brain decline, and the link showed up most clearly in the Mexican American adults Alzheimer's research keeps leaving out.

Brain & Aging

For Twenty Years, Women Were Warned That Estrogen Raised Their Dementia Risk. Stanford's Autopsies Point the Other Way.

A randomized federal trial spent two decades warning that hormone therapy raised older women's dementia risk. A Stanford autopsy study just found the opposite association. The catch: both studied women who started the drug far too late to settle it.

Brain & Aging

A Brain Full of Plaques and a Mind That Held: The Cells That May Explain Alzheimer's Resilient Third

About a third of people whose brains show the full pathology of Alzheimer's never develop dementia. Dutch researchers say the difference may not be how many young neurons they have, but whether those cells switch on a survival program instead of dying.

Brain & Aging

In Mice, Early Stress-Drinking Corroded a Brain Region a Long Sobriety Couldn't Repair

In mice, pairing alcohol with stress in early adulthood damaged a tiny noradrenaline hub in the brainstem, and a prolonged stretch of abstinence didn't reverse it. The cognitive cost surfaced in middle age.

Brain & Aging

For Decades They Treated This Stroke Like a Clog. The Arteries Were Actually Too Wide.

People with widened brain arteries were four times more likely to have had a lacunar stroke, the type doctors have treated for decades as if it were a clog.

Brain & Aging

Alzheimer's Hitches a Ride on a Virus Your Neurons Tamed for Memory

In mice and in human Alzheimer's brains, toxic tau rides a protein called Arc, a virus your neurons domesticated for memory, from sick cells into healthy ones. Delete Arc and the spread nearly stops.

Brain & Aging

A Federally Backed Trial Got High-Dose Fish Oil Into the Brain Fluid. The Memory Scores Never Moved.

DHA in the spinal fluid climbed 17 percent. Cognitive scores rose 2.76 points on fish oil, 2.67 on placebo. Two years of high-dose pills bought a rounding error.

Brain & Aging

A molecule your body already makes coaxed exhausted brain cells back to fighting Alzheimer's

Spanish and Swiss researchers report that OLE, a fatty-acid amino-acid the body already makes, coaxed sluggish microglia to surround amyloid plaques and improve memory in Alzheimer's mice.

Brain & Aging

Brain Gains Into Your 90s Are Probably Real. The Index Measuring Them Has a Patent Pending.

A three-year UT Dallas study tracking nearly 4,000 adults to age 94 says brain function can climb at any age. The biology is plausible. The catch is that the people measuring the gain are the same people patenting the yardstick.